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Mesothelioma and Non Asbestos Exposure

The majority of mesothelioma cases occur on the linings of the lungs and abdomen. The rare cancer may also form in the heart's lining (pericardium) or the testes.

Asbestos exposure is a major risk factor for mesothelioma. However, some people diagnosed with mesothelioma don't have a history of asbestos exposure.

Exposure to Asbestos

Asbestos is a natural mineral that was previously employed in industrial and construction products across the globe. People who worked in asbestos lawsuit industries handled the material on a regular basis and were at risk of exposure. Asbestos particles can be lodged in the lungs, which can lead to progressive lung disease. This is known as asbestosis. As time passes, the asbestos fibers that are trapped in the lungs could cause mesothelioma. Asbestos is also inhaled or ingested, and the risk of developing mesothelioma and other asbestos (click to find out more)-related diseases increases depending on the duration and amount of exposure.

The majority of mesothelioma cases stem from exposure to occupational toxins. Asbestos was utilized in various trades, including construction insulation, electrical work, automobile maintenance and pipefitting. As these trades are dominated by males 75-80% of mesothelioma cases are diagnosed in males. However, the gradual elimination of asbestos case in the United States and other first-world countries has reduced exposure to asbestos on the job. This has resulted in a shift in the number of cases as non-occupational asbestos exposure increasing in frequency.

Non-occupational mesothelioma can occur when asbestos is released from a work environment or in the home or school environment. It can also be caused by exposure to secondhand asbestos, such as when a family member handles the clothing of an exposed asbestos worker. People who are exposed to this kind of exposure might experience symptoms like breathing problems or chest pain that is commonly mistaken for lung or heart conditions.

Certain studies have linked mesothelioma to non-occupational exposure, however the results vary. A majority of these studies were conducted on a limited sample size, and the between-study the degree of heterogeneity is high. It is necessary to conduct further studies to confirm the link between non-occupational asbestos exposure and mesothelioma.

People who have been exposed to non-occupational asbestos should discuss their asbestos medical history with their doctor. If they are concerned, they should ask for a mesothelioma test and a referral to a specialist. Mesothelioma specialists are able to provide patients with the most effective treatment and care options to improve their odds of survival. They will look over medical records and conduct imaging tests to diagnose mesothelioma. They will also provide guidance on how to file a mesothelioma suit to obtain compensation from an asbestos trust fund.

Secondhand Exposure

While asbestos exposure is the main cause of mesothelioma, it's not the only factor that can cause you to develop this disease. In fact, there's some evidence that suggests that people may develop mesothelioma even though they never directly handled asbestos or worked in an industry that involved asbestos-related activities. This is known as secondary or non-occupational asbestos exposure.

Asbestos fibers are extremely small, and they can stick to clothing, hair, skin and other surfaces. This means that workers can bring the dangerous fibers home in their work clothes and transfer them to family members. These stray asbestos fibers can be swallowed or inhaled which can cause mesothelioma.

This type of mesothelioma is more common in women, and it usually occurs in the lung. However, it can also occur in the abdomen or chest wall. The most frequent sign is a shortness of breath (dyspnea), and it is often associated with other symptoms such as fluid in the lungs or swelling in the scrotum.

The mesothelioma which occurs in the lungs is known as mesothelioma of the pleural region. Mesothelioma that is affecting the stomach or chest wall is called mesothelioma of the peritoneal region. A person with this type of mesothelioma can be afflicted by a variety that include abdominal pain, difficulty breathing and constipation.

Several studies have reported that individuals with no previous history of exposure to asbestos can still get mesothelioma because of exposure to asbestos through secondhand fibers. The people who were affected typically resided with someone who was exposed to asbestos. They may have touched the garments of the worker, or they might have had other contact with asbestos.

Veterans are at a high risk of mesothelioma because asbestos was extensively used in military bases, vehicles and ships. The Navy is particularly at risk because asbestos was used to insulate the hull of the ship and to fireproof gun turrets. In addition, sailors frequently brought home asbestos from their jobs aboard ships that were contaminated with asbestos.

Environmental Exposure

A variety of materials have been associated with mesothelioma. Nevertheless, the disease is most often associated with exposure to asbestos. Asbestos is a naturally occurring mineral that was utilized for a number of years in manufacturing. The mineral is heat-resistant and tough, which makes it ideal for use in insulation, brakes, shingles, flooring and other products. When asbestos is broken up, it creates dust that can be breathed in or swallowed. The asbestos fibers can stay in the lungs or stomach for years, and trigger mesothelioma-related symptoms.

The most frequently reported mesothelioma symptoms are breathing difficulties, abdominal pain and chest pain. Asbestos sufferers may suffer from these symptoms for 20 to 60 years or longer after their first exposure. It is essential to consult a doctor when you experience these symptoms. It is also crucial to tell your doctor about your previous history of asbestos. This will prevent the wrong diagnosis and ensure you receive the right treatment.

Mesothelioma that is caused by exposure to asbestos is most common in people who worked directly with asbestos, but it can also affect loved relatives of those who have been exposed. This is referred to as secondary exposure. Family members may inhale or swallow asbestos fibers on a worker's clothes, tools or shoes. They may be exposed to asbestos legal to asbestos by someone who brings home the particles on their clothing or hair. This is why mesothelioma patients and their families must be sure to clean their clothing after working with asbestos.

There is a large amount of research that suggests a relationship between nonasbestos exposure and mesothelioma, but there is no conclusive evidence yet on the role of other agents. For example, there is some evidence that the zeolites erionite as well as chrysotile can cause mesothelioma. Erionite is present in the soil and rocks of certain parts in Turkey where the risk of pleural mesothelioma is high.

Research on the relationship between mesothelioma and nonasbestos exposure is ongoing. Funnel plots have indicated the potential for publication bias, and there is a high degree of heterogeneity between studies. However, it is still clear that occupational exposure to asbestos is the most important risk factor for mesothelioma.

Genetics

Mesothelioma is a rare condition caused by malignant mesothelial cells that grow out of control and invade surrounding tissues. It can also expand throughout the body through traversing the bloodstream or lymphatic system and impacting other organs. Although asbestos is the primary cause of mesothelioma is not the only risk factor. The condition could be triggered by other environmental and genetic factors.

In some instances, mesothelioma has occurred in people who had no direct exposure to asbestos. These are referred to as non-occupational mesothelioma sufferers. They typically experienced indirect exposure through the handling of contaminated clothing or household items by an asbestos-exposed person within their household. For instance, it's possible for one to be diagnosed with pleural mesothelioma as a result of the inhalation of asbestos fibers from a loved one's clothing. Research has shown that these types of mesothelioma cases tend to have longer latency periods and are more likely to be diagnosed in wives than husbands.

Scientists are investigating the possibility that genetic predispositions to mesothelioma may play a role in the development. Recent studies have revealed that mutations in BAP1 gene could increase the risk of mesothelioma developing in people who are exposed to asbestos. This is significant because it could lead improved screening procedures for people who are at risk of developing mesothelioma.

Researchers have identified a variety of genes that are linked to mesothelioma. Some of these genes are involved in reducing the growth of tumors, and are often altered or mutated in mesothelioma sufferers. These genes include the massive tumor suppressor homolog 2 (LATS2) and NF2.

A family history of the disease can increase the risk. This is due to certain genes, like the BAP1 one, can be inherited from a parent. Asbestos was used heavily in the military for a number of years and veterans suffer from the highest mesothelioma rates when compared to other occupational categories. People who were in the Navy and on ships were particularly at greatest risk due to the high exposure to asbestos in fireproofing, insulation materials and shipbuilding.